Author

Francesco Santarelli

University of Luxembourg

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1

Frequent Co-Authors

Anastasia KhvorovaiD· 1 shared Anastasia P. Grigorenko· 1 shared Andrew H. ColesiD· 1 shared Bruno M.D.C. GodinhoiD· 1 shared Chantal M. FergusoniD· 1 shared Dimas EcheverriaiD· 1 shared Evgeny Ivanovich RogaeviD· 1 shared Jacquelyn SousaiD· 1 shared

Activity by Year

2022-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperNeuroscience

Anastasia KhvorovaORCID

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1 paper

Recent·Most cited

Silencing of ApoE with Divalent siRNAs Drives Activation of Immune Clearance Pathways and Improves Amyloid Pathology in Mouse Models of Alzheimer's Disease

Chantal M. Ferguson, Samuel R. Hildebrand, Bruno M.D.C. Godinho, Julianna E. Buchwald, Dimas Echeverria, Andrew H. Coles, Anastasia P. Grigorenko, Lorenc Vanjielli, Jacquelyn Sousa, Nicholas McHugh, Matthew R. Hassler, Francesco Santarelli, Michael Thomas Heneka, Evgeny Ivanovich Rogaev, Anastasia Khvorova

This study shows that silencing ApoE in the brain with divalent siRNAs reduces amyloid plaques in Alzheimer's mice without affecting systemic cholesterol.

bioRxiv · Jun 28, 2022 · PreprintNeuroscience