Early life stress programming of NG2+ glia transcriptome alters functional properties of voltage gated sodium (Nav) channels and cognitive performance
Giulia Treccani, Hatice Yiğit, Thomas Lingner, Vanessa Schleuβner, Franziska Mey, Michael A. van der Kooij, Malin Wennström, David P. Herzog, Matthias Linke, Markus Fricke, Michael J. Schmeißer, Gregers Wegener, Thomas Mittmann, Jacqueline Trotter, Marianne B. Müller
This study shows that early life stress alters the transcriptome of NG2+ glia, increases Nav channel activity, and impairs cognitive performance in adulthood.
Neurobiology of Stress · May 13, 2021Peer-reviewedNeuroscience