Author

Thomas Lingner

Genevention (Germany)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 3 Bioinformatics· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1

Frequent Co-Authors

Marianne B. MülleriD· 2 shared Aaron E. DarlingiD· 1 shared Adrian FritziD· 1 shared Alexander SczyrbaiD· 1 shared Alexey A. GurevichiD· 1 shared Alice Carolyn McHardyiD· 1 shared Andreas BremgesiD· 1 shared Anja UrbachiD· 1 shared

Activity by Year

2017-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersNeuroscience

Marianne B. MüllerORCID

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Author profile →

4 papers

Recent·Most cited

Reconceptualising resilience within a translational framework is supported by unique and brain-region specific transcriptional signatures in mice

Sarah Ayash, Thomas Lingner, Anna Ramisch, Soojin Ryu, Raffaël Kalisch, Ulrich Schmitt, Marianne B. Müller

The paper identifies three phenotypic subgroups of mice following chronic social defeat and finds brain-region specific transcriptional signatures associated with each subgroup.

Proceedings of the National Academy of Sciences · Apr 17, 2023Peer-reviewedNeuroscience

Early life stress programming of NG2+ glia transcriptome alters functional properties of voltage gated sodium (Nav) channels and cognitive performance

Giulia Treccani, Hatice Yiğit, Thomas Lingner, Vanessa Schleuβner, Franziska Mey, Michael A. van der Kooij, Malin Wennström, David P. Herzog, Matthias Linke, Markus Fricke, Michael J. Schmeißer, Gregers Wegener, Thomas Mittmann, Jacqueline Trotter, Marianne B. Müller

This study shows that early life stress alters the transcriptome of NG2+ glia, increases Nav channel activity, and impairs cognitive performance in adulthood.

Neurobiology of Stress · May 13, 2021Peer-reviewedNeuroscience

DNA methyltransferase 1 (DNMT1) function is implicated in the age-related loss of cortical interneurons

Anne Hahn, Cathrin Bayer, Daniel Pensold, Jessica Tittelmeier, Lisa Marx-Blümel, Lourdes González-Bermúdez, Jenice Linde, Jonas Groß, Gabriela Salinas, Thomas Lingner, Julia von Maltzahn, Marc Spehr, Tomas Pieler, Anja Urbach, Geraldine Zimmer‐Bensch

This study shows that DNMT1 deletion in interneurons reduces age-related loss of cortical interneurons and improves somatomotor performance in mice.

Frontiers in Cell and Developmental Biology · Jul 22, 2020Peer-reviewedNeuroscience

Critical Assessment of Metagenome Interpretation - a benchmark of computational metagenomics software

Alexander Sczyrba, Peter Hofmann, Peter Belmann, David Koslicki, Stefan Janssen, Johannes Dröge, Ivan Gregor, Stephan Majda, Jessika Fiedler, Eik Dahms, Andreas Bremges, Adrian Fritz, Rubén Garrido‐Oter, Tue Sparholt Jørgensen, Nicole Shapiro, , Alice Carolyn McHardy

The paper benchmarks computational metagenomics software using complex datasets, showing strengths and limitations in assembly, binning, and taxonomic profiling.

Nature Methods · Oct 2, 2017Peer-reviewedBioinformatics