Author

Frederik Eikens

Max-Planck-Institute for Biology of Ageing, Cologne, Germany;

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Henrich· 1 shared Annett Halle· 1 shared Hannah Scheiblich· 1 shared Lena Erlebach· 1 shared Lena Wischhof· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Anna Henrich

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1 paper

Recent·Most cited

Inflammatory proteostasis reprogramming creates a lysosomal bottleneck for microglial aggregate clearance

Frederik Eikens, Lena Wischhof, Anna Henrich, Lena Erlebach, Annett Halle, Hannah Scheiblich

This study shows that inflammatory activation impairs microglial degradation of protein aggregates by creating a lysosomal bottleneck, without affecting their uptake.

bioRxiv · Nov 3, 2026 · PreprintCell Biology