Author

Lena Wischhof

Max-Planck-Institute for Biology of Ageing, Cologne, Germany;Primary ORCID profile (0000-0002-2203-408X · 1 paper)Unclaimed ORCID profile · follow to get notified of new preprints

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Lena WischhofiD1 paper · Max Planck Institute for Biology of Ageing

Biology Disciplines

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Cell Biology· 1

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Anna Henrich· 1 shared Annett Halle· 1 shared Frederik Eikens· 1 shared Hannah Scheiblich· 1 shared Lena Erlebach· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

5 top collaborators · 10 mutual co-author links

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1 shared paperCell Biology

Anna Henrich

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1 paper

Recent·Most cited

Inflammatory proteostasis reprogramming creates a lysosomal bottleneck for microglial aggregate clearance

Frederik Eikens, Lena Wischhof, Anna Henrich, Lena Erlebach, Annett Halle, Hannah Scheiblich

This study shows that inflammatory activation impairs microglial degradation of protein aggregates by creating a lysosomal bottleneck, without affecting their uptake.

bioRxiv · Nov 3, 2026 · PreprintCell Biology