Author

Freya Hoddle

The Francis Crick Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

André OharaiD· 1 shared Anna CioceiD· 1 shared Benjamin SchumanniD· 1 shared Carme RoviraiD· 1 shared Carolyn Ruth BertozziiD· 1 shared Ganka Bineva‐ToddiD· 1 shared Karen Marie PolizziiD· 1 shared Kevin J. BruemmeriD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

André OharaORCID

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1 paper

Recent·Most cited

Iterative Bump-and-hole engineering creates a bioorthogonal reporter for N-acetylglucosaminyltransferase I

Liu Yu, Saskia Pieters, Ganka Bineva‐Todd, Mert Sagiroglugil, Sean A. Burnap, Freya Hoddle, Anna Cioce, André Ohara, Sophie D. Schmidt, Kevin J. Bruemmer, Carolyn Ruth Bertozzi, Karen Marie Polizzi, Weston B. Struwe, Carme Rovira, Benjamin Schumann

The paper develops a bioorthogonal reporter for MGAT1 by iteratively engineering a UDP-GlcNAc analog with a chemical tag, enabling specific substrate incorporation in mammalian cells.

Journal of the American Chemical Society · Jun 30, 2026Peer-reviewedBiochemistry