HIV-1 interactions with sialic acid-binding bacterial lectins promote virus infectivity in vitro and mucosal transmission in humanized mice
Clauvis Kunkeng Yengo, Xiaomei Liu, Ries J. Langley, Frida Avila, Manish Sagar, Christina Ochsenbauer, Barbara A. Bensing, Catarina E. Hioe
This study shows that sialic acid-binding bacterial lectins enhance HIV-1 infectivity in vitro and mucosal transmission in humanized mice by promoting virus-cell attachment and spread.
Frontiers in Cellular and Infection Microbiology · Sep 16, 2026Peer-reviewedMicrobiology