eIF3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex
Colin Echeverría Aitken, Petra Beznosková, Vladislav Vlčkova, Wen-Ling Chiu, Fujun Zhou, Leoš Shivaya Valášek, Alan G Hinnebusch, Jon R Lorsch
The paper investigates eIF3's roles in mRNA recruitment to the ribosomal preinitiation complex by analyzing functional variants in yeast, revealing distinct roles at entry and exit channels.
eLife · Oct 26, 2016Peer-reviewedBiochemistry