Cancer BiologybioRxiv
Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma
H.-H. Lu, S.-Y. Lin, R. R. Weng…·H.-C. Tsai
This study identifies FUT4 as a key driver of lung adenocarcinoma metastasis through aberrant fucosylation of proteins involved in cell signaling and trafficking, showing its potential as a therapeutic target.
DOI 10.1016/j.ebiom.2020.102846