Author

H.-C. Tsai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cancer & tumor microenvironment· 2 Organism:mouse· 2 Assay:proteomics· 2 Assay:ATAC-seq· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

C.-J. Yu· 2 shared H.-H. Lu· 2 shared J.-C. Liao· 2 shared R. R. Weng· 2 shared S.-Y. Lin· 2 shared T.-Y. Chiu· 2 shared Y.-H. Juan· 2 shared Y.-J. Huang· 2 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCancer Biology

C.-J. Yu

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

INPP5E regulates CD3ζ enrichment at the immune synapse by phosphoinositide distribution control

T.-Y. Chiu, F.-H. Yang, W. M. Chong, H.-C. Tsai, W.-J. Wang, J.-C. Liao

This study shows INPP5E regulates CD3ζ localization at the immune synapse by controlling phosphoinositide distribution, affecting TCR signaling and IL-2 secretion.

bioRxiv · Jan 6, 2021Cell Biology

Epigenetic therapy remodels the immune synaptic cytoskeleton to potentiate cancer susceptibility to γδ T cells

R. R. Weng, H.-H. Lu, C.-T. Lin, C.-C. Fan, R.-S. Lin, T.-C. Huang, S.-Y. Lin, Y.-J. Huang, Y.-H. Juan, Y.-C. Wu, Z.-C. Hung, C. Liu, X.-H. Lin, W.-C. Hsieh, T.-Y. Chiu, , H.-C. Tsai

DNA methyltransferase inhibitors enhance γδ T cell-mediated lung cancer killing by remodeling immune synaptic cytoskeletal networks.

bioRxiv · Apr 30, 2020 · PreprintCancer Biology

Fucosyltransferase 4 shapes oncogenic glycoproteome to drive metastasis of lung adenocarcinoma

H.-H. Lu, S.-Y. Lin, R. R. Weng, Y.-H. Juan, Y.-W. Chen, H.-H. Hou, Z.-C. Hung, G. A. Oswita, Y.-J. Huang, J.-Y. Shih, C.-J. Yu, H.-C. Tsai

This study identifies FUT4 as a key driver of lung adenocarcinoma metastasis through aberrant fucosylation of proteins involved in cell signaling and trafficking, showing its potential as a therapeutic target.

bioRxiv · Nov 11, 2019Cancer Biology

Naa10p promotes metastasis by stabilizing matrix metalloproteinase-2 protein in human osteosarcomas

M.-H. Chien, W.-J. Lee, Y.-C. Yang, P. Tan, K.-F. Pan, H.-C. Tsai, C.-H. Hsu, M. Hsiao, K.-T. Hua

This study shows Naa10p promotes osteosarcoma metastasis by stabilizing MMP-2 protein through N-terminal acetylation.

bioRxiv · Jan 5, 2018Cancer Biology