Author
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
10 papers
Recent·Most cited
L. G. Denaro, S.-Y. Lin, C.-y. Huang
This paper develops Y-Net, a deep learning model that estimates 10 tea flavor-related compounds using spectral data from fresh tea shoots, outperforming other models and showing promise for quality monitoring.
bioRxiv · Mar 5, 2024Biochemistry
C.-W. Chen, P.-Y. Lin, Y.-M. Lai, M.-H. Lin, S.-Y. Lin, C.-C. Hsu
TIMAHAC enables high-throughput simultaneous analysis of plant phosphoproteomics and N-glycoproteomics, identifying 1,954 N-glycopeptides and 11,255 phosphopeptides in Arabidopsis under ABA treatment.
bioRxiv · Feb 26, 2024Biochemistry
H.-M. Wu, N.-J. Huang, Y. V. Yang, L.-P. Fan, T.-Y. Tang, L. Liu, Y. Xu, D.-T. Liu, Z.-X. Cai, X.-Y. Ren, Z.-H. Yao, J.-Z. Chen, X. Huang, C. Zhang, X. You, , S.-Y. Lin
This study shows probucol reduces high-fat diet-induced cognitive and social impairments in mice without affecting obesity or metabolic homeostasis, by disrupting redox-inflammation links.
bioRxiv · Sep 5, 2023Animal Behavior & Cognition
R.-H. Wang, P.-R. Chen, Y.-T. Chen, Y.-C. Chen, Y.-H. Chu, C.-C. Chien, P.-C. Chien, S.-Y. Lo, Z.-L. Wang, M.-C. Tsou, S.-Y. Chen, G.-S. Chiu, W.-L. Chen, Y.-H. Wu, L. Wang, , K.-T. Lin
This study shows hydrogen sulfide destabilizes PKM2 tetramer through sulfhydration at cysteine 326, rewiring glucose metabolism and inhibiting tumor growth.
bioRxiv · Sep 2, 2023Cancer Biology
M. Li, Y. Wang, X. Wei, W.-F. Cai, M. Zhu, L. Yao, Y. Wang, Y.-H. Liu, J. Wu, J. Xiong, X. Tian, Q. Qu, R. Xie, X. Li, S. Chen, , S.-C. Lin
This paper identifies AMPK's role in shifting carbon utilization from glucose to glutamine via PDZD8 phosphorylation, enhancing glutaminolysis and extending lifespan in C. elegans and mice.
bioRxiv · Jul 20, 2023 · PreprintCell Biology
C.-W. Chen, C.-F. Tsai, M.-H. Lin, S.-Y. Lin, C.-C. Hsu
The paper develops a tandem S-Trap-IMAC method for plant phosphoproteomics, improving coverage and quantification accuracy in Arabidopsis.
bioRxiv · Feb 23, 2023 · PreprintBiochemistry
F. Pan, S.-X. Yu, X. Wang, H.-C. Huang, Z.-Y. Cai, J.-M. Wang, S.-Y. Lin, Y.-L. Gao, E.-M. Li, L.-Y. Xu
The paper characterizes epigenetic alterations in esophageal cancer using whole-genome bisulfite sequencing and identifies novel clusters and molecular features in two subtypes.
bioRxiv · Dec 5, 2021 · PreprintCancer Biology
R. Xu, K. Wang, Z. Yao, L. Jin, J. Pang, Y. Zhou, K. Wang, D. Liu, Y. Zhang, P. Sun, F. Wang, x. Chang, Y. Li, S. Wang, Y. Zhang, , X. Han
This study shows Brsk2 amplifies parasympathetic signals to promote type 2 diabetes by enhancing β-cell insulin secretion in obese mice and associates human BRSK2 variants with metabolic disorders.
bioRxiv · Aug 5, 2021 · PreprintPathology
R. R. Weng, H.-H. Lu, C.-T. Lin, C.-C. Fan, R.-S. Lin, T.-C. Huang, S.-Y. Lin, Y.-J. Huang, Y.-H. Juan, Y.-C. Wu, Z.-C. Hung, C. Liu, X.-H. Lin, W.-C. Hsieh, T.-Y. Chiu, , H.-C. Tsai
DNA methyltransferase inhibitors enhance γδ T cell-mediated lung cancer killing by remodeling immune synaptic cytoskeletal networks.
bioRxiv · Apr 30, 2020 · PreprintCancer Biology
H.-H. Lu, S.-Y. Lin, R. R. Weng, Y.-H. Juan, Y.-W. Chen, H.-H. Hou, Z.-C. Hung, G. A. Oswita, Y.-J. Huang, J.-Y. Shih, C.-J. Yu, H.-C. Tsai
This study identifies FUT4 as a key driver of lung adenocarcinoma metastasis through aberrant fucosylation of proteins involved in cell signaling and trafficking, showing its potential as a therapeutic target.
bioRxiv · Nov 11, 2019Cancer Biology