Sequence, Structure and Context Preferences of Human RNA Binding Proteins
D. Dominguez, P. Freese, M. S. Alexis, A. Su, M. Hochman, T. Palden, C. Bazile, N. J. Lambert, E. L. Van Nostrand, G. A. Pratt, G. W. Yeo, B. Graveley, C. B. Burge
The paper presents affinity landscapes of 78 human RNA binding proteins using deep sequencing to determine sequence, structure, and context preferences, revealing patterns of low motif diversity and contextual feature preferences.
bioRxiv · Oct 12, 2017Biochemistry