Author

C. B. Burge

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Evolutionary Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 5 Assay:bulk RNA-seq· 4 Approach:experimental assay· 4 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:statistical model· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Dominguez· 2 shared M. S. Alexis· 2 shared A. Su· 1 shared B. E. Begg· 1 shared B. Graveley· 1 shared C. Bazile· 1 shared E. L. Van Nostrand· 1 shared F. F. Cavazos· 1 shared

Activity by Year

2017-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersEvolutionary Biology

D. Dominguez

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Author profile →

5 papers

Recent·Most cited

Understanding species-specific and conserved RNA-protein interactions in vivo and in vitro

S. E. Harris, M. S. Alexis, G. Giri, F. F. Cavazos, J. Murn, M. M. Aleman, C. B. Burge, D. Dominguez

The paper examines interspecies differences in RNA-protein interactions using the neuronal RNA binding protein UNK, finding conserved binding patterns and species-specific sequence determinants.

bioRxiv · Jan 29, 2024 · PreprintEvolutionary Biology

Quantifying negative selection in human 3' UTRs uncovers constrained targets of RNA-binding proteins

S. D. Findlay, L. Romo, C. B. Burge

The paper identifies 3' UTR variants under negative selection using gnomAD data and iMAPS, revealing constrained sites for RNA-binding proteins and polyadenylation signals.

bioRxiv · Nov 30, 2022Evolutionary Biology

Sensory nerves enhance triple-negative breast cancer migration and metastasis via the axon guidance molecule PlexinB3

T. T. Le, S. L. Payne, M. N. Buckwald, L. A. Hayes, C. B. Burge, M. Oudin

This study shows sensory nerves promote TNBC migration and metastasis through PlexinB3-mediated adhesion and gene expression changes.

bioRxiv · Dec 7, 2021 · PreprintCancer Biology

Secondary motifs enable concentration-dependent regulation by Rbfox family proteins

B. E. Begg, M. Jens, P. Y. Wang, C. B. Burge

This study identifies secondary RNA motifs that enable Rbfox proteins to regulate splicing at lower concentrations, expanding beyond the canonical GCAUG motif.

bioRxiv · Nov 12, 2019 · PreprintBiochemistry

Sequence, Structure and Context Preferences of Human RNA Binding Proteins

D. Dominguez, P. Freese, M. S. Alexis, A. Su, M. Hochman, T. Palden, C. Bazile, N. J. Lambert, E. L. Van Nostrand, G. A. Pratt, G. W. Yeo, B. Graveley, C. B. Burge

The paper presents affinity landscapes of 78 human RNA binding proteins using deep sequencing to determine sequence, structure, and context preferences, revealing patterns of low motif diversity and contextual feature preferences.

bioRxiv · Oct 12, 2017Biochemistry