Author

G. B. Evans

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Research Focus:protein folding & dynamics· 1 Assay:protein sequence· 1

Frequent Co-Authors

D. F. Ackerley· 1 shared E. M. M. Bulloch· 1 shared E. M. Williams· 1 shared J. Copp· 1 shared K. J. Robins· 1 shared K. R. Hall· 1 shared K. Sparrow· 1 shared L. D. Harris· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperBiochemistry

D. F. Ackerley

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2 papers

Recent·Most cited

Inhibition of the DENV2 and ZIKV RNA polymerases by Galidesivir triphosphate measured using a continuous fluorescence assay

S. Deshpande, W. Huo, R. Shrestha, K. Sparrow, G. B. Evans, L. D. Harris, R. L. Kingston, E. M. M. Bulloch

This paper measures the inhibition of DENV2 and ZIKV RNA polymerases by Galidesivir triphosphate using a continuous fluorescence assay, finding it equipotent against both with IC50 values of 42 and 47 M.

bioRxiv · Dec 20, 2022Microbiology

A giant leap in sequence space reveals the intracellular complexities of evolving a new function

K. R. Hall, K. J. Robins, M. H. Rich, M. J. Calcott, J. Copp, E. M. Williams, R. F. Little, R. Schwörer, G. B. Evans, W. M. Patrick, D. F. Ackerley

The paper evolves an enzyme to detoxify chloramphenicol, revealing that endogenous substrates significantly influence evolutionary trajectories through epistatic interactions.

bioRxiv · May 27, 2020 · PreprintBiochemistry