Author

G. Carnell

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Organism:multiple species· 1

Frequent Co-Authors

N. Temperton· 3 shared F. Ferrara· 2 shared S. Scott· 2 shared A. Huckriede· 1 shared A. Pessi· 1 shared C. A.M. de Haan· 1 shared D. Corti· 1 shared D. J. Kelvin· 1 shared

Activity by Year

2018-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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3 shared papersMicrobiology

N. Temperton

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Author profile →

4 papers

Recent·Most cited

The bat influenza H17N10 can be neutralized by broadly-neutralizing monoclonal antibodies and its neuraminidase can facilitate viral egress.

G. Carnell, E. Giotis, K. Grehan, F. Ferrara, S. Mather, E. Molesti, S. Scott, A. Pessi, K. Lacek, N. Temperton

This paper shows that bat influenza H17N10 can be neutralized by human antibodies and its neuraminidase N10 aids viral release without using sialic acid as a receptor.

bioRxiv · Jan 12, 2019 · PreprintMicrobiology

The MHC class-II HLA-DR receptor mediates bat influenza A-like H17N10 virus entry into mammalian cells

E. S. Giotis, G. Carnell, E. F. Young, S. Ghanny, P. Soteropoulos, W. S. Barclay, M. A. Skinner, N. Temperton

This study identifies HLA-DR as a receptor for bat influenza A-like H17N10 virus entry into mammalian cells, revealing a novel mechanism distinct from classical influenza A viruses.

bioRxiv · Jan 4, 2019Microbiology

Development and use of Lentiviral Vectors Pseudotyped with Influenza B Haemagglutinins: application to vaccine immunogenicity, mAb potency and sero-surveillance studies

F. Ferrara, G. Carnell, R. Kinsley, E. Bottcher-Friebertshauser, S. Pohlmann, S. Scott, S. Fereidouni, D. Corti, P. Kellam, S. Gilbert, N. J. Temperton

The paper develops influenza B haemagglutinin-pseudotyped lentiviral vectors as sensitive tools for detecting neutralizing and cross-reactive antibodies in vaccine and sero-surveillance studies.

bioRxiv · Dec 10, 2018 · PreprintMicrobiology

Cross-protective immune responses induced by sequential influenza virus infection and by sequential vaccination with inactivated influenza vaccines

W. Dong, Y. Bhide, F. Sicca, T. Meijerhof, K. Guilfoyle, O. G. Engelhardt, L. Boon, C. A.M. de Haan, G. Carnell, N. Temperton, J. de Vries-Idema, D. J. Kelvin, A. Huckriede

This study shows that sequential vaccination with inactivated influenza vaccines can reduce pandemic virus infection severity, while subunit vaccines cannot, through cross-reactive antibodies and CD8+ T cells.

bioRxiv · May 31, 2018Microbiology