P. Soteropoulos

Comprehensive analysis of disease pathology in immunocompetent and immunocompromised hamster models of SARS-CoV-2 infection

This study compares SARS-CoV-2 infection outcomes in immunocompetent and immunocompromised hamsters, finding that histopathological changes better predict disease severity than viral load or antibody levels.

Phase variation in Mycobacterium tuberculosis glpK produces transiently heritable drug tolerance

This paper identifies a novel mechanism of drug tolerance in M. tuberculosis through phase variation in the glpK gene, showing reversible frameshift mutations that contribute to treatment failure and relapse.

The MHC class-II HLA-DR receptor mediates bat influenza A-like H17N10 virus entry into mammalian cells

This study identifies HLA-DR as a receptor for bat influenza A-like H17N10 virus entry into mammalian cells, revealing a novel mechanism distinct from classical influenza A viruses.