Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease
A. Douangamath, D. Fearon, P. Gehrtz, T. Krojer, P. Lukacik, C. D. Owen, E. Resnick, C. Strain-Damerell, A. aimon, P. Abranyi-Balogh, J. Brandao-Neto, A. Carberry, G. Davison, A. Dias, T. D. Downes, , M. A. Walsh
The paper identifies fragment hits against SARS-CoV-2 main protease using crystallography and mass spectrometry, revealing structural insights for drug design.
bioRxiv · May 27, 2020Biophysics