A stable leading strand polymerase/clamp loader complex is required for normal and perturbed eukaryotic DNA replication
K. Stokes, A. Winczura, B. Song, G. De Piccoli, D. B. Grabarczyk
This study identifies the role of Ctf18-RFC in DNA replication by showing its interaction with DNA Pol ε and its function in fork protection and checkpoint signaling.
bioRxiv · Oct 17, 2019Biochemistry