G. Goeminne

Integrating multiple omics levels using the human protein complexome as a framework, a multi-omics study of inborn errors of metabolism

This study integrates proteomics, transcriptomics, and metabolomics data from IEM patients to identify perturbed protein complexes and pathways, highlighting mitochondrial oxidative phosphorylation and histone acetylation dysregulation.

The selective estrogen receptor modulator clomiphene inhibits sterol biosynthesis in Arabidopsis thaliana

The paper identifies clomiphene, a selective estrogen receptor modulator, as an inhibitor of plant sterol biosynthesis by targeting CPI1, suggesting its potential for agricultural applications.

Compensatory guaiacyl lignin biosynthesis at the expense of syringyl lignin in 4CL1-knockout poplar

Knockout of 4CL1 in Populus reveals a 4CL5-dependent compensatory pathway for lignification with links to thiol redox balance and sulfur assimilation.