Cancer BiologybioRxivPreprint
The PAXFOXO1s trigger fast trans-differentiation of chick embryonic neural cells into alveolar rhabdomyosarcoma with tissue invasive properties limited by S phase entry inhibition
G. GONZALEZ CURTO, A. Der Vartanian, Y. FRARMA…·V. RIBES
This study shows PAXFOXO1 fusion proteins drive neural cells to become ARMS-like cells but are limited by G1 cell cycle arrest, which can be overcome by CYCLIN D1 or MYCN.
DOI 10.1101/2020.05.18.097618