MicrobiologybioRxivPreprint
Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects
K. P. Gopalakrishna, G. H. Hillebrand, V. H. Bhavana…·T. A. Hooven
The paper investigates how GBS Cas9 variants affect genome-wide transcription and shows nonspecific protospacer adjacent motif binding drives these effects without altering virulence.
DOI 10.1101/2023.05.24.542094