Author

H. Tettelin

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 4 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1

Frequent Co-Authors

A. D'Mello· 4 shared J. L. Elder· 2 shared K. P. Gopalakrishna· 2 shared N. J. Weyand· 2 shared A. B. Chamby· 1 shared A. J. Catomeris· 1 shared A. J. Ratner· 1 shared A. N. Dammann· 1 shared

Activity by Year

2020-2023 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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4 shared papersMicrobiology

A. D'Mello

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Unveiling the Immune Dynamics of Neisseria Persistent Oral Colonization: A Roadmap for Innovative Vaccine Strategies

M. Alles, M. Gunasena, T. Zia, A. D'Mello, S. Saroj Bhattarai, W. Mulhern, L. Terry, T. Scherger, S. Wijeratne, S. Singh, A. Wijeratne, D. Kasturiratna, H. Tettelin, N. J. Weyand, N. Liyanage

This study investigates immune dynamics during Neisseria musculi colonization in mice, identifying key genes and pathways for immune homeostasis and offering insights for vaccine development.

bioRxiv · Dec 18, 2023 · PreprintImmunology

Group B Streptococcus Cas9 variants provide insight into programmable gene repression and CRISPR-Cas transcriptional effects

K. P. Gopalakrishna, G. H. Hillebrand, V. H. Bhavana, J. L. Elder, A. D'Mello, H. Tettelin, T. A. Hooven

The paper investigates how GBS Cas9 variants affect genome-wide transcription and shows nonspecific protospacer adjacent motif binding drives these effects without altering virulence.

bioRxiv · May 24, 2023 · PreprintMicrobiology

Influenza A virus modulation of Streptococcus pneumoniae infection using ex vivo transcriptomics in a human primary lung epithelial cell model reveals differential host glycoconjugate uptake and metabolism

A. D'Mello, J. R. Lane, J. L. Tipper, E. Martinez, H. N. Roussey, K. S. Harrod, C. J. Orihuela, H. Tettelin

This study uses ex vivo transcriptomics to show that influenza A virus infection enhances pneumococcal growth and alters bacterial metabolism in human lung epithelial cells.

bioRxiv · Jan 29, 2023 · PreprintMicrobiology

In vitro phenotypic and transcriptomic variation in Neisseria musculi morphotypes correlate with colonization variability and persistence in vivo

E. Thapa, L. Lauderback, C. Simmons, D. L. Holzschu, A. D'Mello, M. Ma, M. So, H. Tettelin, N. J. Weyand

This study compares in vitro and in vivo phenotypes of two Neisseria musculi morphotypes, showing differences in colonization patterns and persistence in mice.

bioRxiv · Feb 3, 2022 · PreprintMicrobiology

MrvR, a group B Streptococcus transcription factor that controls multiple virulence traits

A. N. Dammann, A. B. Chamby, A. J. Catomeris, K. M. Davidson, H. Tettelin, J. P. van Pijkeren, K. P. Gopalakrishna, M. F. Keith, J. L. Elder, A. J. Ratner, T. Hooven

This paper identifies MrvR, a GBS transcription factor that enhances survival in amniotic fluid and virulence traits, through Tn-seq, CRISPRi, and transcriptomic analysis.

bioRxiv · Nov 17, 2020Microbiology