Role of necroptosis in chronic hepatic inflammation and liver disease in Cu/Zn superoxide dismutase deficient mice
S. Mohammed, E. H. Nicklas, N. Thadathil, R. Selvarani, G. H. Royce, A. Richardson, S. S. Deepa
This study shows that necroptosis contributes to liver inflammation, fibrosis, and HCC progression in Sod1KO mice by increasing pro-inflammatory markers and STAT3 activation.
bioRxiv · Aug 17, 2020 · PreprintBiochemistry