Author

G. J. Pazour

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 4

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 4 Approach:experimental assay· 3 Research Focus:development & morphogenesis· 2 Organism:mouse· 2 Research Focus:protein folding & dynamics· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1

Frequent Co-Authors

B. Lv· 2 shared B. Huang· 1 shared D. Doherty· 1 shared F. P. Cordelieres· 1 shared G. Garcia· 1 shared J. C. Van De Weghe· 1 shared J. F. Reiter· 1 shared M. W. Stuck· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

B. Lv

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Regulation of Hedgehog Signaling Through Arih2-Mediated Smoothened Ubiquitination and Endoplasmic Reticulum-Associated Degradation

B. Lv, X.-O. Zhang, G. J. Pazour

This study identifies Arih2-mediated Smo ubiquitination and ERAD as critical regulators of Hedgehog signaling, showing that Arih2{beta} prevents mislocalized Smo from disrupting pathway activity.

bioRxiv · Feb 20, 2022 · PreprintCell Biology

Ubiquitin Links Smoothened to Intraflagellar Transport to Regulate Hedgehog Signaling

P. B. Desai, M. W. Stuck, B. Lv, G. J. Pazour

The paper shows that ubiquitination regulates Smo's ciliary levels by linking it to intraflagellar transport, controlling Hedgehog signaling.

bioRxiv · Dec 18, 2019Cell Biology

Uncoupling Intraflagellar Transport and Primary Cilia Formation Demonstrates Deep Integration of IFT in Hedgehog Signaling

T. Eguether, F. P. Cordelieres, G. J. Pazour

The paper shows IFT is involved in hedgehog signaling dynamics but not required for smoothened delivery to cilia.

bioRxiv · Nov 28, 2017Cell Biology

Super-Resolution Microscopy Reveals That Disruption Of Ciliary Transition Zone Architecture Is A Cause Of Joubert Syndrome

X. Shi, G. Garcia, J. C. Van De Weghe, R. McGorty, G. J. Pazour, D. Doherty, B. Huang, J. F. Reiter

This study uses super-resolution microscopy to show that mutations in RPGRIP1L and TCTN2 disrupt transition zone architecture in Joubert syndrome, affecting ciliary protein localization and signaling.

bioRxiv · May 25, 2017Cell Biology