Author

P. B. Desai

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

A. B. Marquez· 1 shared A. Karve· 1 shared A. M. Baschnagel· 1 shared B. Lv· 1 shared C. Wang· 1 shared D. Bhatacharya· 1 shared D. Ionascu· 1 shared D. K. Toukam· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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1 shared paperBioengineering

A. B. Marquez

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3 papers

Recent·Most cited

GABA(A) receptor activation drives GABARAP-Nix mediated autophagy to radiation-sensitize primary and brain-metastatic lung adenocarcinoma tumors

D. Bhatacharya, R. Barille, D. K. Toukam, V. S. Gawali, L. Kallay, T. Ahmed, H. Brown, S. Rezvanian, A. Karve, P. B. Desai, M. Medvedovic, K. Wang, D. Ionascu, N. Harun, C. Wang, , S. Sengupta

This paper shows that activating GABA(A) receptors in lung cancer cells triggers autophagy via GABARAP-Nix interaction, enhancing radiation sensitivity and reducing toxicity in preclinical models.

bioRxiv · Nov 29, 2023Cancer Biology

3-D Vascularized Breast Cancer Model to Study the Role of Osteoblast in Formation of a Pre-Metastatic Niche

R. Rimal, P. B. Desai, A. B. Marquez, K. Sieg, Y. Marquardt, S. Singh

This paper develops a 3-D vascularized breast cancer model to study osteoblast influence on tumor progression and identifies gene expression changes associated with pre-metastatic niche formation.

bioRxiv · May 5, 2021Bioengineering

Ubiquitin Links Smoothened to Intraflagellar Transport to Regulate Hedgehog Signaling

P. B. Desai, M. W. Stuck, B. Lv, G. J. Pazour

The paper shows that ubiquitination regulates Smo's ciliary levels by linking it to intraflagellar transport, controlling Hedgehog signaling.

bioRxiv · Dec 18, 2019Cell Biology