Author

G. L. Parkman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 2 Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

M. W. VanBrocklin· 2 shared W. J. Burnett· 2 shared A. Cluff· 1 shared A. Ramstead· 1 shared C. Hart· 1 shared C. M. Stehn· 1 shared D. A. Kircher· 1 shared D. H. Lum· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersImmunology

M. W. VanBrocklin

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2 papers

Recent·Most cited

Human Rhinoviruses: a novel class of oncolytic virus

W. J. Burnett, A. Cluff, M. Reeves, G. L. Parkman, C. Hart, A. Ramstead, S. Holmen, M. A. Williams, M. W. VanBrocklin

This study investigates wild-type human rhinoviruses (HRVs) as oncolytic viruses, showing their ability to kill cancer cells and induce tumor regression in vitro and in vivo.

bioRxiv · May 31, 2023 · PreprintImmunology

Genetic silencing of AKT induces melanoma cell death

G. L. Parkman, T. Turapov, D. A. Kircher, W. J. Burnett, C. M. Stehn, K. T. O'Toole, R. Flaherty, R. C. Elmer, K. M. Culver, M. Foth, R. Andtbacka, D. H. Lum, R. L. Judson-Torres, M. W. VanBrocklin, S. L. Holmen, M. McMahon

This study shows that genetic silencing of AKT paralogs in melanoma cells leads to cell death via mTORC signaling disruption, which can be rescued by activated SGK1, suggesting dual targeting of AKT and SGK1 as a potential therapy.

bioRxiv · Aug 15, 2022 · PreprintCancer Biology