Cohesin mediates DNA loop extrusion and sister chromatid cohesion by distinct mechanisms
K. Nagasaka, I. F. Davidson, R. Stocsits, W. Tang, G. Wutz, P. Batty, M. Panarotto, G. Litos, A. Schleiffer, D. W. Gerlich, J. M. Peters
This study shows cohesin uses distinct mechanisms for DNA loop extrusion and sister chromatid cohesion, and that CTCF boundary interactions may rely on related mechanisms.
bioRxiv · Sep 23, 2022Cell Biology