The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle
A. E. N. Aristodemou, D. S. Rueda, G. P. Taylor, C. R. M. Bangham
This study uses bulk RNA-seq to analyze host gene expression changes during HTLV-1 reactivation in primary CD4+ T cells, identifying Polycomb gene expression shifts and deubiquitinases that promote proviral transcription.
bioRxiv · Jan 8, 2023Microbiology