D. S. Rueda

Substrate accessibility regulation of human TopIIa decatenation by cohesin

This study investigates how TOP2 resolves DNA braids and shows cohesin inhibits its activity by preventing substrate access.

The transcriptome of HTLV-1-infected primary cells following reactivation reveals changes to host gene expression central to the proviral life cycle

This study uses bulk RNA-seq to analyze host gene expression changes during HTLV-1 reactivation in primary CD4+ T cells, identifying Polycomb gene expression shifts and deubiquitinases that promote proviral transcription.

Condensin compacts DNA in 15 nm steps and requires FACT for extrusion on chromatin

The paper was withdrawn due to issues with two figures, and the authors do not wish it to be cited.

Single-molecule analysis reveals cooperative stimulation of Rad51 filament nucleation and growth by mediator proteins

The paper uses single-molecule imaging to show how BRC-2 and RFS-1/RIP-1 mediate RAD-51 filament nucleation and growth during homologous recombination.

Live Cell Imaging of Single RNA Molecules with Fluorogenic Mango II Arrays

This paper introduces a novel Mango II aptamer array for high-contrast, single-molecule RNA imaging in live and fixed cells, showing improved signal-to-noise ratio and compatibility with super-resolution microscopy.

Retroviral integration into nucleosomes throughDNA looping and sliding along the histone octamer

This study reveals that retroviral integrase uses a looping-and-sliding mechanism to reposition nucleosomal DNA for integration, similar to chromatin remodelers.