C. S. Greene

Molecular subtypes of high grade serous ovarian cancer across racial groups and gene expression platforms

This study identifies molecular subtypes of high-grade serous ovarian cancer across racial groups and gene expression platforms, finding similar subtype-specific survival rates despite differences in subtype prevalence.

Integration of 168,000 samples reveals global patterns of the human gut microbiome

The paper integrates 168,484 human gut microbiome samples to reveal global patterns, showing widespread presence of Firmicutes and regional differences in microbial genera.

Analysis of Pseudomonas aeruginosa transcription in an ex vivo cystic fibrosis sputum model identifies metal restriction as a gene expression stimulus

The paper analyzes Pseudomonas aeruginosa gene expression in CF sputum and identifies metal restriction as a key driver of gene expression variation across donors.

A publishing infrastructure for AI-assisted academic authoring

This paper explores using AI to improve scholarly writing by integrating large language models into a publishing ecosystem, showing they can enhance text clarity through revisions.

The Field-Dependent Nature of PageRank Values in Citation Networks

This study examines how field-specific citation norms affect PageRank values in citation networks and suggests field-aware metrics may better capture manuscript importance.

Changing word meanings in biomedical literature reveal pandemics and new technologies

The paper analyzes semantic shifts in biomedical preprints and peer-reviewed texts, identifying terms like 'cas9' and 'pandemic' that changed meaning, with a focus on the impact of the COVID-19 pandemic.

Computationally efficient assembly of a Pseudomonas aeruginosa gene expression compendium

The paper processes and normalizes thousands of Pseudomonas aeruginosa RNA-seq datasets to enable cross-experiment comparisons and hypothesis testing.

Analysis of science journalism reveals gender and regional disparities in coverage

This study analyzes science journalism to reveal gender and regional disparities in coverage, finding a male skew in quotes but faster progress toward gender equality compared to authorship.

Single-cell transcriptomic profile reveals macrophage heterogeneity in medulloblastoma and their treatment-dependent recruitment

The paper uses single-cell and bulk RNA sequencing to study macrophage heterogeneity in medulloblastoma and shows differential recruitment with targeted vs. radiation therapy.

Pseudomonas aeruginosa lasR mutant fitness in microoxia is supported by an Anr-regulated oxygen-binding hemerythrin

This paper identifies an Anr-regulated hemerythrin, Mhr, that enhances fitness of Pseudomonas aeruginosa lasR mutants in microoxic conditions by binding oxygen.

Integrated Phosphoproteomics and Transcriptional Classifiers Reveal Hidden RAS Signaling Dynamics in Multiple Myeloma

The paper uses phosphoproteomics and transcriptomics to analyze RAS signaling in multiple myeloma, identifying distinct signaling patterns and clinical outcomes associated with NRAS and KRAS mutations.