G. S. Singaraju

Transient interactions drive the lateral clustering of Cadherin-23 on membrane

This study shows that transient hydrophobic interactions drive lateral clustering of cadherin-23 on membranes, enhancing cell adhesion without requiring specific cis-dimer interactions.

Molecular mechanism of cell-cell adhesion mediated by cadherin-23

This study identifies a novel antiparallel-binding interface of cadherin-23 homodimer and shows how mutations in this interface affect cell-cell adhesion and cancer.