Author

G. Sapkal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 8 Immunology· 1

Signature Assays, Organisms & Methods

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Research Focus:host-pathogen & immune response· 9 Approach:experimental assay· 8 Organism:human· 4 Organism:mouse· 4 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1

Frequent Co-Authors

P. Abraham· 8 shared G. Deshpande· 7 shared D. Y. Patil· 5 shared N. Gupta· 5 shared P. D. Yadav· 5 shared S. Mohandas· 5 shared A. Kumar· 4 shared B. Bhargava· 4 shared

Activity by Year

2021-2022 · peak 6/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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8 shared papersMicrobiology

P. Abraham

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Protective efficacy of COVAXIN(R) against Delta and Omicron variants in hamster model

P. Yadav, S. Mohandas, A. Shete, G. Sapkal, G. Deshpande, A. Kumar, K. Wakchaure, H. Dighe, R. Jain, B. Ganneru, J. Yemul, P. Gawande, K. M. Vadrevu, P. Abraham

This study evaluates COVAXIN's protective efficacy against Delta and Omicron variants in hamsters, showing improved protection with a third dose and reduced disease severity.

bioRxiv · Jun 14, 2022Immunology

Substantial immune response in Omicron infected breakthrough and unvaccinated individuals against SARS-CoV-2 variants of concerns

P. D. Yadav, G. Sapkal, R. R. Sahay, V. Potdar, G. Deshpande, D. Y. Patil, D. A. Nyayanit, A. M. Shete, J. Shastri, P. Awate, B. Malhotra, P. Abraham

This study compares IgG and neutralizing antibody responses in vaccinated and unvaccinated individuals infected with the Omicron variant of SARS-CoV-2, showing reduced neutralization against Omicron compared to earlier variants.

bioRxiv · Jan 24, 2022Microbiology

Pathogenicity of SARS-CoV-2 Omicron in Syrian hamsters and its neutralization with different Variants of Concern

S. Mohandas, P. D. Yadav, G. Sapkal, A. M. Shete, G. Deshpande, D. A. Nyayanit, D. Y. Patil, M. Kadam, A. Kumar, C. Mote, R. Jain

This study evaluates the pathogenicity of SARS-CoV-2 Omicron BA.1 in Syrian hamsters and finds reduced cross-neutralization against other variants.

bioRxiv · Jan 19, 2022 · PreprintMicrobiology

Neutralization of Delta variant with sera of Covishield vaccinees and COVID-19 recovered vaccinated individuals

G. Sapkal, P. D. Yadav, R. R. Sahay, G. Deshpande, N. Gupta, D. A. Nyayanit, D. Y. Patil, S. Kumar, P. Abraham, S. Panda, B. Bhargava

This study evaluates immune response in Covishield vaccinated and recovered individuals against the Delta variant, finding higher protection in breakthrough cases and recovered individuals compared to single or double vaccinated groups.

bioRxiv · Jul 1, 2021Microbiology

Neutralization against B.1.351 and B.1.617.2 with sera of COVID-19 recovered cases and vaccinees of BBV152

P. D. Yadav, G. Sapkal, R. Ella, R. R. Sahay, D. A. Nyayanit, D. Y. Patil, G. Deshpande, A. M. Shete, N. Gupta, V. K. Mohan, P. Abraham, S. Panda, B. Bhargava

This study assesses the neutralization efficacy of sera from COVID-19 recovered cases and BBV152 vaccinees against SARS-CoV-2 variants B.1.351 and B.1.617.2, showing reduced titers but still protective responses.

bioRxiv · Jun 5, 2021 · PreprintMicrobiology

Isolation of SARS-CoV-2 B.1.1.28.2 P2 variant and pathogenicity comparison with D614G variant in hamster model

P. Yadav, S. Mohandas, P. Sarkale, D. Nyayanit, A. Shete, R. Sahay, V. Potdar, S. Baradkar, N. Gupta, G. Sapkal, P. Abraham, S. Panda, B. Bhargava

The paper isolates the SARS-CoV-2 B.1.1.28.2 (P.2) variant from travelers and compares its pathogenicity to the D614G variant in hamsters, finding it more severe and with reduced neutralization.

bioRxiv · May 24, 2021Microbiology

Neutralization of B.1.1.28 P2 variant with sera of natural SARS-CoV-2 infection and recipients of BBV152 vaccine

G. Sapkal, P. Yadav, R. Ella, P. Abraham, D. Patil, N. Gupta, S. Panda, K. M. V, B. Bhargava

This study evaluates the neutralizing efficacy of B.1.1.28.2 variant against sera from natural infection and BBV152 vaccine recipients, showing reduced neutralization compared to D614G.

bioRxiv · Apr 30, 2021 · PreprintMicrobiology

Comparison of the pathogenicity and virus shedding of SARS CoV-2 VOC 202012/01 and D614G variant in hamster model

S. Mohandas, P. D. Yadav, D. Nyayanit, G. Deshpande, A. S. Aich, G. Sapkal, S. Kumar, R. Jain, M. Kadam, A. Kumar, D. Y. Patil, P. Sarkale, P. Gawande, P. Abraham

This study compares the pathogenicity and virus shedding of SARS-CoV-2 VOC 202012/01 and D614G variants in hamsters, finding higher viral shedding and mild lung pathology with VOC 202012/01.

bioRxiv · Feb 25, 2021 · PreprintMicrobiology

Assessment of immunogenicity and protective efficacy of ZyCoV-D DNA vaccine candidates in Rhesus macaques against SARS-CoV-2 infection

P. Yadav, S. Kumar, K. Agarwal, M. Jain, D. Patil, K. Maithal, B. Mathapati, S. Giri, S. Mohandas, A. Shete, G. Sapkal, D. Patil, A. Dey, H. Chandra, G. Deshpande, , P. Abraham

This study evaluates two doses of ZyCoV-D DNA vaccine in rhesus macaques, finding that the 2mg dose via Needle Free Injection System provides better immune response and protection against SARS-CoV-2.

bioRxiv · Feb 2, 2021 · PreprintMicrobiology