G. T. Montelione

The paper evaluates AlphaFold models of small proteins against experimental NMR and X-ray structures, finding they match or exceed NMR accuracy.

The paper develops a hybrid MELD-NMR approach to determine structures of flexible protein-polypeptide complexes using only NMR chemical shift data, achieving accurate results for ET domain-BET protein interactions.

The paper investigates structural evolution of DsrAB across sulfate-reducing organisms, identifying conserved features and allostery-related co-variance patterns.

This study characterizes YhcB, a conserved gamma-proteobacterial protein, showing it is essential for cell division and envelope integrity through genetic, structural, and interaction analyses.

This paper evaluates HCV protease inhibitors as potential SARS-CoV-2 antivirals, finding that simeprevir and grazoprevir synergize with remdesivir to enhance antiviral activity against SARS-CoV-2 in cell culture.

This paper investigates the structural interactions of the BRD3 ET domain with host and viral proteins, revealing polymorphic structural interfaces and conformational plasticity.