PhysiologybioRxivPreprint
Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction
M. Wohlwend, P.-P. Laurila, L. Goeminne…·J. Auwerx
This study shows that reducing CERS1 in skeletal muscle worsens age-related muscle dysfunction in mice and humans, linking it to inflammation and fibrosis.