Author

L. Goeminne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Approach:genetic perturbation / CRISPR· 1 Organism:mouse· 1

Frequent Co-Authors

J. Auwerx· 2 shared A. Awani· 1 shared A. DeVilbiss· 1 shared B. Crisol· 1 shared D. Dever· 1 shared G. Benegiamo· 1 shared G. von Alvensleben· 1 shared H. Gallart-Ayala· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersPhysiology

J. Auwerx

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Author profile →

2 papers

Recent·Most cited

Inhibition of CERS1 in skeletal muscle exacerbates age-related muscle dysfunction

M. Wohlwend, P.-P. Laurila, L. Goeminne, T. Lima, I. Daskalaki, X. Li, G. von Alvensleben, B. Crisol, R. Mangione, H. Gallart-Ayala, O. Burri, S. Butler, J. Morris, N. Turner, J. Ivanisevic, J. Auwerx

This study shows that reducing CERS1 in skeletal muscle worsens age-related muscle dysfunction in mice and humans, linking it to inflammation and fibrosis.

bioRxiv · Aug 5, 2023 · PreprintPhysiology

Reticular Dysgenesis-associated Adenylate Kinase 2 deficiency causes failure of myelopoiesis through disordered purine metabolism

W. Wang, A. DeVilbiss, M. Arreola, T. Mathews, Z. Zhao, M. Martin-Sandoval, G. Benegiamo, A. Awani, L. Goeminne, D. Dever, Y. Nakauchi, M. Pavel-Dinu, W. Al-Herz, L. Noratangelo, M. H. Porteus, , K. G. Weinacht

This study shows AK2 deficiency disrupts mitochondrial metabolism, causing purine metabolism disorder and myelopoiesis failure through AMP accumulation and NAD+ depletion.

bioRxiv · Jul 5, 2021 · PreprintCell Biology