Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling
E. Min, N. Baeyens, R. Hu, Z. Zhuang, M. Chen, B. Huang, G. Zarkada, A. Acheampong, K. McEntee, M. Simons, A. Eichmann, M. Schwartz
This study shows that low shear stress activates Smad 2/3 signaling in endothelial cells, leading to inward artery remodeling.
bioRxiv · Jul 5, 2019 · PreprintCell Biology