Z. Zhuang

PHOSPHATE-INDUCED 1 and its paralogs positively regulate cellulose biosynthesis in Arabidopsis.

This study shows that PHOSPHATE-INDUCED 1 and its paralogs regulate cellulose biosynthesis in Arabidopsis by modulating CSC activity in response to developmental and environmental cues.

SntB triggers the antioxidant pathways to regulate development and aflatoxin biosynthesis in Aspergillus flavus

This study identifies SntB as a regulator of growth, development, and aflatoxin biosynthesis in Aspergillus flavus by modulating antioxidant pathways and gene expression.

"Tumor Treating Fields" delivered via electromagnetic induction have varied effects across glioma cell lines and electric field amplitudes

This study applies electromagnetic fields to glioma cell lines and finds variable effects on proliferation and gene expression, contradicting previous in vitro findings of consistent anti-proliferative effects.

Cell transcriptomic atlas of the non-human primate Macaca fascicularis

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

Global Spatial Transcriptome of Macaque Brain at Single-Cell Resolution

The paper creates a 3-D cell type atlas of the monkey brain using single-cell spatial transcriptomics and identifies molecular markers for neocortical layers and subregions.

In vivo co-registered hybrid-contrast imaging by successive photoacoustic tomography and magnetic resonance imaging

This paper presents a hardware-software solution for co-registering photoacoustic tomography and MRI images in vivo, demonstrating hybrid-contrast imaging of tumor microenvironments.

Rapid development of SARS-CoV-2 receptor binding domain-conjugated nanoparticle vaccine candidate

This study designs and tests RBD-conjugated nanoparticle vaccines against SARS-CoV-2, showing enhanced neutralizing activity compared to monomeric RBD.

Single-cell Multi-omics reveal heterogeneity and metastasis potential in different liver cancer cell lines

The paper uses single-cell multi-omics to analyze HCC cell lines, identifying metastasis potential heterogeneity and a hypoxic subgroup with poor prognosis.

Single-cell atlas of a non-human primate reveals new pathogenic mechanisms of COVID-19

This study creates a single-cell transcriptome atlas of a non-human primate to explore SARS-CoV-2 targets and immune responses, identifying potential therapeutic targets and mechanisms linking IL6 to viral entry.

Activation of Smad 2/3 signaling by low shear stress mediates artery inward remodeling

This study shows that low shear stress activates Smad 2/3 signaling in endothelial cells, leading to inward artery remodeling.

A Single-Cell Immune Atlas of Triple Negative Breast Cancer Reveals Novel Immune Cell Subsets

The paper performs single-cell RNA sequencing on TNBC tumors to identify novel immune cell subsets and their associations with survival and TCR signaling.

Fibronectin receptor integrin α5β1 regulates assembly of PP2A complexes through PDE4D: modulation of vascular inflammation and atherosclerosis

This study shows that integrin α5β1 regulates PP2A complex assembly via PDE4D5, reducing vascular inflammation and atherosclerosis in mice.