The RNA m6A reader YTHDF1 promotes hematopoietic malignancy by maintaining oncogenic translation
X. Gao, Z. Chen, Y.-G. Hong, Z. Yang, Y. Chen, T. Liu, Y. Zheng, G.-C. Wu, Y. Chen, J. Xia, R. Wen, Y. Zhao, J. Chen
This study identifies YTHDF1 as an oncogenic m6A reader promoting AML by enhancing oncogenic translation and shows tegaserod inhibits its function.
bioRxiv · Oct 8, 2022 · PreprintCancer Biology