Author

R. Wen

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. A. Griffith· 1 shared A. Salomon· 1 shared C. R. Bertozzi· 1 shared D. S. Roberts· 1 shared E. E. Peterson· 1 shared E. Handy· 1 shared G. Fu· 1 shared G. M. Stepek· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperBiochemistry

A. A. Griffith

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Tumor Immune Cell Targeting Chimeras (TICTACs) reprogram tumor-associated macrophages

M. Morimoto, D. S. Roberts, R. Wen, E. Handy, E. E. Peterson, G. M. Stepek, N. A. Till, J. D. Brooks, C. R. Bertozzi

The paper develops TICTACs, which selectively target and degrade checkpoint receptors on tumor-associated macrophages without affecting other cells.

bioRxiv · Dec 6, 2023 · PreprintBiochemistry

The RNA m6A reader YTHDF1 promotes hematopoietic malignancy by maintaining oncogenic translation

X. Gao, Z. Chen, Y.-G. Hong, Z. Yang, Y. Chen, T. Liu, Y. Zheng, G.-C. Wu, Y. Chen, J. Xia, R. Wen, Y. Zhao, J. Chen

This study identifies YTHDF1 as an oncogenic m6A reader promoting AML by enhancing oncogenic translation and shows tegaserod inhibits its function.

bioRxiv · Oct 8, 2022 · PreprintCancer Biology

Mouse primary T cell phosphotyrosine proteomics enabled by BOOST

X. Y. Chua, K. P. Callahan, A. A. Griffith, T. Hildebrandt, G. Fu, M. Hu, R. Wen, A. Salomon

The paper applies the BOOST method to perform phosphotyrosine proteomics on mouse primary T cells, demonstrating improved quantitation depth and accuracy by disabling the ΦSDM parameter in Orbitrap instruments.

bioRxiv · May 13, 2022 · PreprintBiochemistry