Marfan Patient iPSC-Derived Endothelial Cells Carrying FBN1 Variants Reveal Endothelial Dysfunction
Philipp Christoph Hauger, Gabija Danilinaite, Leonardo Spagnolello, Carsten Tobias Kuenne, Max C. Overboom, Jan Willem Buikema, Vivian de Waard, Peter Lodewijk Hordijk
This study uses iPSC-derived endothelial cells from Marfan syndrome patients to show impaired inflammatory resolution and endothelial dysfunction linked to FBN1 variants.
bioRxiv · Aug 21, 2026 · PreprintCell Biology