Author

Gabriella Angelini

Broad Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:cell type annotation· 1 Assay:CRISPR screen· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1 Research Focus:software / tool· 1

Frequent Co-Authors

Alyssa Pyclik· 1 shared Amanda Beccard· 1 shared Angelica MessanaiD· 1 shared Daisy LamiD· 1 shared Dane Z. HazelbakeriD· 1 shared Huanying Gary Ge· 1 shared John R. LydeardiD· 1 shared Juliana M. Xavier-FerrucioiD· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioinformatics

Alyssa Pyclik

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Author profile →

2 papers

Recent·Most cited

A resource and computational approach for quantifying gene editing allelism at single-cell resolution

Matthew H. Ung, Gabriella Angelini, Ruijia Wang, Alyssa Pyclik, John R. Lydeard, Juliana M. Xavier-Ferrucio, Michelle I. Lin, Tirtha Chakraborty, Huanying Gary Ge

The paper constructs a single-cell DNA sequencing atlas and introduces GUMM, a computational workflow, to accurately infer gene editing allelism despite technical artifacts.

bioRxiv · May 22, 2025 · PreprintBioinformatics

Multiplexed and Inducible Gene Modulation in Human Pluripotent Stem Cells by CRISPR Interference and Activation

Dane Z. Hazelbaker, Amanda Beccard, Gabriella Angelini, Patrizia Mazzucato, Angelica Messana, Daisy Lam, Kevin C. Eggan, Lindy E. Barrett

The paper develops a stable, multiplexed CRISPRi/a system in hPSCs using fluorescent piggyBac vectors and inducible dCas9 transgenes to enable precise gene modulation and analysis.

Scientific Reports · Jan 20, 2020Peer-reviewedMolecular Biology