Dysregulation of an H3K79me2-dependent epigenetic barrier impairs neural progenitor cell proliferation and differentiation in Fragile X syndrome
Olivier Dionne, Gabrielle-Lee Gaudreau, Clara Bergis, Mariano Avino, Salomé Sabatié, François Corbin, Benoît Laurent
This study identifies an H3K79me2-dependent epigenetic barrier in FXS neural progenitor cells, showing its dysregulation impairs proliferation and differentiation.
bioRxiv · Aug 31, 2025 · PreprintNeuroscience