Author

Olivier Dionne

Université de SherbrookeORCID 0000-0002-0531-9761Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:ChIP-seq· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

Benoît LaurentiD· 2 shared Bo O. ZhouiD· 1 shared Clara BergisiD· 1 shared François CorbiniD· 1 shared Gabrielle-Lee Gaudreau· 1 shared Jacqueline I. KimiD· 1 shared Jeru Manoj ManueliD· 1 shared Joannie St-Germain· 1 shared

Activity by Year

2025-2025 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersNeuroscience

Benoît LaurentORCID

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2 papers

Recent·Most cited

Dysregulation of an H3K79me2-dependent epigenetic barrier impairs neural progenitor cell proliferation and differentiation in Fragile X syndrome

Olivier Dionne, Gabrielle-Lee Gaudreau, Clara Bergis, Mariano Avino, Salomé Sabatié, François Corbin, Benoît Laurent

This study identifies an H3K79me2-dependent epigenetic barrier in FXS neural progenitor cells, showing its dysregulation impairs proliferation and differentiation.

bioRxiv · Aug 31, 2025 · PreprintNeuroscience

A neuron-specific microexon ablates the novel DNA-binding function of a histone H3K4me0 reader PHF21A

Robert S. Porter, Sojin An, María Cecilia Gavilán, Masayoshi Nagai, Yumie Murata-Nakamura, Bo O. Zhou, Katherine M. Bonefas, Olivier Dionne, Jeru Manoj Manuel, Joannie St-Germain, Suzanne Gascon, Jacqueline I. Kim, Liam Browning, Benoît Laurent, Uhn‐Soo Cho, Shigeki Iwase

The paper identifies neuron-specific microexon splicing in chromatin regulators, showing that PHF21A loses DNA-binding function in neurons while retaining H3K4me0 recognition, contributing to brain development.

Cell Reports · Jan 1, 2025Peer-reviewedMolecular Biology