Single Cell-type Integrative Network Modeling IdentifiedNovel Microglial-specific Targets for the Phagosome inAlzheimer's disease
Kruti Rajan Patel, Kuixi Zhu, Marc Henrion, Noam D. Beckmann, Sara Moein, Melissa L. Alamprese, Mariet Allen, Xue Wang, Gail Chan, Thomas Pertel, Parham Nejad, Joseph S. Reddy, Minerva M. Carrasquillo, David Alan Bennett, Nilüfer Ertekin‐Taner, , Rui R. Chang
The paper develops a computational systems biology approach to identify novel microglial-specific targets for the phagosome in Alzheimer's disease using integrated transcriptome and genotype data.
bioRxiv · Jun 9, 2020 · PreprintSystems Biology