Author

Sara Moein

University of Arizona

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2 Molecular Biology· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

David Alan BennettiD· 3 shared Kuixi ZhuiD· 3 shared Marc HenrioniD· 3 shared Melissa L. AlampreseiD· 3 shared Nilüfer Ertekin‐TaneriD· 3 shared Rui R. ChangiD· 3 shared Branden Lau· 2 shared Philip L. De JageriD· 2 shared

Activity by Year

2020-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersNeuroscience

David Alan BennettORCID

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Author profile →

4 papers

Recent·Most cited

Targeted sequencing of mutations via RNA-templated gap filling of oligonucleotides for single-cell RNA-seq

Mirca Saras Saurty-Seerunghen, Hower Lee, Martha Holdar, Kellie Wise, Michael J. Roach, Sara Moein, Ted Kang, Taobo Hu, Mats F. Nilsson, Luciano Gastón Martelotto, Anna S. Nam, Marco Grillo

This paper introduces a method for targeted sequencing of expressed mutations in single cells using RNA-templated gap filling with BstFL polymerase, enabling simultaneous transcriptomic and mutation profiling.

bioRxiv · Apr 12, 2026 · PreprintMolecular Biology

Predictive Network Analysis Identifies JMJD6 and Other Novel Key Drivers in Alzheimer Disease

Julie P. Merchant, Kuixi Zhu, Marc Henrion, Syed Shujaat Ali Zaidi, Branden Lau, Sara Moein, Melissa L. Alamprese, Richard V. Pearse, David Alan Bennett, Nilüfer Ertekin‐Taner, Tracy L. Young‐Pearse, Rui R. Chang

The paper identifies JMJD6 and other key drivers of Alzheimer's disease using predictive network analysis and validates their effects on amyloid-beta and tau pathology in human neurons.

bioRxiv · Oct 19, 2022 · PreprintNeuroscience

Novel Master Regulators of Microglial Phagocytosis and Repurposed FDA-approved Drug for Treatment of Alzheimer Disease

Kuixi Zhu, Qianying He, Sheng‐Feng Tsai, Dinusha C. Maheepala, Marc Henrion, Syed Shujaat Ali Zaidi, Branden Lau, Andrew Tang, Mika P. Cadiz, Rachel Hodos-Nkhereanye, Sara Moein, Melissa L. Alamprese, David Alan Bennett, Philip L. De Jager, John D. Frye, , Rui R. Chang

The paper identifies key driver genes for microglial phagocytosis and repurposes riluzole to treat Alzheimer's Disease by enhancing SLC1A2 activity.

bioRxiv · Oct 19, 2022 · PreprintNeuroscience

Single Cell-type Integrative Network Modeling IdentifiedNovel Microglial-specific Targets for the Phagosome inAlzheimer's disease

Kruti Rajan Patel, Kuixi Zhu, Marc Henrion, Noam D. Beckmann, Sara Moein, Melissa L. Alamprese, Mariet Allen, Xue Wang, Gail Chan, Thomas Pertel, Parham Nejad, Joseph S. Reddy, Minerva M. Carrasquillo, David Alan Bennett, Nilüfer Ertekin‐Taner, , Rui R. Chang

The paper develops a computational systems biology approach to identify novel microglial-specific targets for the phagosome in Alzheimer's disease using integrated transcriptome and genotype data.

bioRxiv · Jun 9, 2020 · PreprintSystems Biology