Author

Parham Nejad

Agios Pharmaceuticals (United States)

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Genomics· 1 Systems Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:simulation· 1

Frequent Co-Authors

Philip L. De JageriD· 2 shared Afsana SabriniD· 1 shared Cristin AubiniD· 1 shared Daniel FelskyiD· 1 shared Daniel HuiiD· 1 shared David Alan BennettiD· 1 shared Elizabeth M. BradshawiD· 1 shared Eric E. SchadtiD· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersGenomics

Philip L. De JagerORCID

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2 papers

Recent·Most cited

Cell type- and state- resolved immune transcriptomic profiling identifies glucocorticoid-responsive molecular defects in multiple sclerosis T cells

Tina Roostaei, Afsana Sabrin, Pia Kivisäkk, Cristin Aubin, Parham Nejad, Daniel Felsky, Hanane Touil, Ioannis S. Vlachos, Daniel Hui, Jennifer Fransson, Nikolaos A. Patsopoulos, Vijay Kumar Kuchroo, Violetta Zujovic, Howard L. Weiner, Hans‐Ulrich Klein, Philip L. De Jager

The paper identifies glucocorticoid-responsive molecular defects in MS T cells through cell-type-specific transcriptomic profiling and validates potential therapeutic targets.

bioRxiv · Jun 29, 2022 · PreprintGenomics

Single Cell-type Integrative Network Modeling IdentifiedNovel Microglial-specific Targets for the Phagosome inAlzheimer's disease

Kruti Rajan Patel, Kuixi Zhu, Marc Henrion, Noam D. Beckmann, Sara Moein, Melissa L. Alamprese, Mariet Allen, Xue Wang, Gail Chan, Thomas Pertel, Parham Nejad, Joseph S. Reddy, Minerva M. Carrasquillo, David Alan Bennett, Nilüfer Ertekin‐Taner, , Rui R. Chang

The paper develops a computational systems biology approach to identify novel microglial-specific targets for the phagosome in Alzheimer's disease using integrated transcriptome and genotype data.

bioRxiv · Jun 9, 2020 · PreprintSystems Biology