Author
University of ArizonaORCID 0000-0001-7950-8920Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Jay M. Yarbro, Xian Han, Abhijit Dasgupta…·Junmin Peng
Alzheimer's mouse model proteomes capture 30% (amyloid-only models) to 42% (adding tau and splicing models) of consensus human AD protein changes; in 5xFAD, plaques slow degradation of plaque-associated proteins.
Julie P. Merchant, Kuixi Zhu, Marc Henrion…·Rui R. Chang
The paper identifies JMJD6 and other key drivers of Alzheimer's disease using predictive network analysis and validates their effects on amyloid-beta and tau pathology in human neurons.
Kuixi Zhu, Qianying He, Sheng‐Feng Tsai…·Rui R. Chang
The paper identifies key driver genes for microglial phagocytosis and repurposes riluzole to treat Alzheimer's Disease by enhancing SLC1A2 activity.
Kruti Rajan Patel, Kuixi Zhu, Marc Henrion…·Rui R. Chang
The paper develops a computational systems biology approach to identify novel microglial-specific targets for the phagosome in Alzheimer's disease using integrated transcriptome and genotype data.
Matthias Arnold, Kwangsik T. Nho, Alexandra Kueider‐Paisley…·Gabi Kastenmüller
The paper investigates sex and APOE ε4 genotype effects on metabolic alterations in Alzheimer’s disease using stratified analysis of serum metabolites.