Infiltrative classical monocyte-derived and SPP1 lipid-associated macrophages mediate inflammation and fibrosis in ANCA-associated glomerulonephritis
Yosta Vegting, Aldo Jongejan, Annette E. Neele, Nike Claessen, Gal Sela, Koen H.M. Prange, Jesper Kers, Joris J. T. H. Roelofs, Joost W van der Heijden, Onno J. de Boer, Ester B. M. Remmerswaal, Liffert Vogt, Fréderike J. Bemelman, Menno P.J. de Winther, Perry D. Moerland, Marc L. Hilhorst
This paper identifies specific macrophage subsets in ANCA-associated glomerulonephritis that drive inflammation and fibrosis, suggesting therapeutic targets.
Nephrology Dialysis Transplantation · Dec 16, 2024Peer-reviewedImmunology