Jesper Kers

CPMsi is a computational pipeline that efficiently processes and integrates large-scale MSI data, enabling faster analysis and discovery of molecular patterns across tissue sections.

This study shows that chronic low-concentration PM2.5 exposure after ischemic injury accelerates CKD through mitochondrial dysfunction and lysosomal stress, with nicotinamide reversing some effects.

This study validates the use of kidney biopsy transport medium for rapid gene profiling to enable same-day molecular diagnosis of kidney disease.

This paper validates a mass spectrometry-based proteomics workflow for kidney transplant biopsies, showing high repeatability and clinical relevance of protein analysis.

This study shows that normothermic kidney preservation with red blood cells causes iron accumulation and ferroptosis, leading to kidney injury, and suggests alternatives to mitigate these effects.

This paper identifies specific macrophage subsets in ANCA-associated glomerulonephritis that drive inflammation and fibrosis, suggesting therapeutic targets.

This study shows human NK cells can activate inflammasomes in vitro and in transplant patients, with distinct responses in CD56 subsets and sustained activation in renal dysfunction and transplant rejection.