Author

Garnett A. Mingledorff

University of Virginia

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Assay:imaging· 1 Organism:mouse· 1

Frequent Co-Authors

George S. BloomiD· 2 shared Ammasi PeriasamyiD· 1 shared Andrés NorambuenaiD· 1 shared Anna J. Mendelson· 1 shared Danielle C. Llaneza· 1 shared Elizabeth R. SharlowiD· 1 shared Evelyn PardoiD· 1 shared Horst K. Wallrabe· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

George S. BloomORCID

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2 papers

Recent·Most cited

Mitochondrial NADK2-dependent NADPH controls Tau oligomer uptake in human neurons

Evelyn Pardo, Taylor Kim, Horst K. Wallrabe, Kristine E. Zengeler, Vijay Kumar Sagar, Garnett A. Mingledorff, Xuehan Sun, Ammasi Periasamy, John R. Lukens, George S. Bloom, Andrés Norambuena

The paper shows that mitochondrial NADK2-dependent NADPH synthesis mediates Tau oligomer uptake in neurons via LRP1, creating a cycle that exacerbates TauO toxicity.

Alzheimer s & Dementia · Jun 1, 2026Peer-reviewedNeuroscience

Extracellular cues accelerate neurogenesis of induced pluripotent stem cell derived neurons

Elizabeth R. Sharlow, Danielle C. Llaneza, Anna J. Mendelson, Garnett A. Mingledorff, Veronica M. Porterfield, Kathryn A. Salvati, Mark P. Beenhakker, George S. Bloom, John Stephen Lazo

This study accelerates and standardizes the maturation of iPSC-derived neurons by optimizing extracellular cues, resulting in synchronized neurogenesis and earlier calretinin expression.

bioRxiv · Aug 17, 2021 · PreprintNeuroscience